The study 'Persistent epigenetic memory of SARS-CoV-2 mRNA vaccination in monocyte-derived macrophages' led ... of messenger substances, so-called cytokines, that can activate numerous immune ...

The study, "Persistent epigenetic memory of SARS-CoV-2 mRNA vaccination in monocyte-derived macrophages ... of messenger substances, so-called cytokines, that can activate numerous immune ...

Investigators hypothesized that this virus is lethal because it induces an unusually potent proinflammatory cytokine response. They infected human monocyte-derived macrophages in vitro with H5N1 ...

This was accompanied by heightened secretion of proinflammatory cytokines such as IL (interleukin)-6 and ... differentiated primary human monocyte-derived macrophages (hMDMs) exposed to homogenates of ...

Following liver injury, the release of DAMPs or PAMPs activates KCs and monocyte-derived macrophages, which in turn release pro-inflammatory cytokines such as TNF-α and IL-1β. These cytokines ...

Results Applied an optimized immune-related cytokine trigger that simulates the effect of ... Additionally, IECs derived from human intestinal organoids were integrated with monocyte-derived ...

However, due to the immunosuppressive factors present in the TME primarily mediated by Myeloid-Derived ... cytokines, T-cell exclusion, and inhibition of T-cell activation. APC, Antigen Presenting ...

In this application note, explore how scientists can couple a serum-free medium with a xeno-free serum replacement to effectively culture functional monocyte-derived dendritic cells and macrophages.