In this application note, explore how scientists can couple a serum-free medium with a xeno-free serum replacement to effectively culture functional monocyte-derived dendritic cells and macrophages.

Significantly, the study examines how these obesity patterns influence brain morphology, function and cognition in middle-aged and older adults, offering deeper insights into their long-term ...

Objective We aimed at investigating the effects of biliary epithelial cell-derived acute phase response protein orosomucoid 2 (ORM2) in shaping monocyte/macrophage response to liver injury. Design ...

Background and purpose: The relationship between peripheral blood monocyte count and primary gross tumor volume with survival prognosis in newly diagnosed nasopharyngeal carcinoma(NPC) patients who ...

To our surprise, though, this synthetic hunger state also led to a marked drop in specific immune cells in the blood, called monocytes. These cells are part of the immune system’s first line of ...

Remarkably, within hours, they saw a fast reorganization of immune cells in the blood, with a noticeable drop in inflammatory monocytes. These artificially hungry mice looked, from an immune ...

These tissue-specific effects were secondary to reduced neutrophil infiltration, modulation of fibroblast activation and phenotype (in the heart) and attenuation of monocyte and macrophage numbers (in ...

There’s also CT-1119, a mesothelin-targeted CAR-monocyte Carisma had been teeing up for a phase 1 trial in China in combination with BeiGene and Novartis’ tislelizumab in patients with ...

Circulating monocytes largely contribute to macrophage buildup in atheromata, which is crucial for clearing subendothelial LDLs (low-density lipoproteins) and dead cells; however, the transitional ...

This can now be tested in larger clinical trials based on these study results. The researchers analyzed monocytes – a type of white blood cells that can differentiate into macrophages in humans – in ...