Summary: Rasagiline is a novel, investigational propargylamine that irreversibly and selectively inhibits monoamine oxidase type B (MAO-B). Rasagiline demonstrates complete and selective ...

Since methylene blue inhibits monoamine oxidase A, there is a risk for a dangerous increase in serotonin levels, manifesting as symptoms such as confusion, muscle twitching, elevated body ...

The team specifically proposed strategies such as introducing heterologous enzyme reactions derived from other organisms and exchanging cofactors used by microbes to expand metabolic pathways.

Shih, Heinz-Josef Lenz. Monoamine oxidase B: a potential therapeutic target for colorectal cancer [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2025; Part ...

These medicines differ in the types of bipolar symptoms they treat. Depakote and Tegretol, for example, tend to be more effective in treating mania than depressive symptoms while Lamictal appears ...

Usually, an enzyme called diamine oxidase (DAO) breaks down histamine. However, different factors can inhibit the activity or expression of this enzyme. A deficiency of DAO typically occurs due to ...

A 67 year old woman taking a monoamine oxidase inhibitor (MAOI) presented to the accident and emergency department with an anaphylactic reaction to flucloxacillin. This case highlights the uncertainty ...

Polyphenols – a range of compounds found naturally in plants – are celebrated for the multitude of health advantages they offer. They are renowned for their antioxidant properties and have ...

Without functional MOCS1, the body cannot produce the intermediate compound cyclic pyranopterin monophosphate (cPMP), leading to a blocked molybdenum cofactor (MoCo) metabolic pathway. This blockage ...