BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately ...

Researchers have revealed critical insights into how impaired mitochondrial dynamics and quality control mechanisms in skeletal muscle influence insulin sensitivity in patients with Type 2 ...

The research team, led by Pennington Biomedical Executive Director Dr. John Kirwan, focused on the significance of deubiquitinating enzymes, or DUBs, in regulating mitochondrial dynamics within ...

Bantam Pharmaceutical, a drug discovery and development company targeting selective modulation of mitochondrial dynamics in cancer, today announced that its Trial in Progress abstract has been ...

Auxilium Biotechnologies, a leader in regenerative medicine, is pleased to announce the enrollment of the first patient in its clinical trial evaluating the safety and efficacy of NeuroSpan BridgeTM, ...

This fundamental study combines in vitro reconstitution experiments and molecular dynamics simulations to elucidate how membrane lipids are transported from the outer to the inner membrane of ...

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An international team of researchers has discovered how cholesterol can disrupt the internal functioning of the heart by ...

An extensive Ca 2+-signalling toolkit is used to assemble cell-specific signalling systems that have very different spatial and temporal dynamics ... such as exocytosis, mitochondrial redox ...

By analyzing ancient and modern DNA, scientists are uncovering the genetic origins of the Greek people, shaped over millennia ...