New research published in Nature Communications into hidden mutations in mitochondrial DNA has uncovered how high mutational ...

into Adobe Illustrator as vector-graphic objects for figure construction and placement. Minor modifications to text alignment, font sizes and positioning of final figures were undertaken strictly to ...

The cages and objects were cleaned with 75% ... of cells expressing 7000 genes and cells with mitochondrial gene content >25%. Unsupervised clustering was carried out using the Seurat package and the ...

Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care, have discovered how mitochondria influence the body's immune response through modulating specific cell signaling ...

Bits of genes that typically reside in mitochondria insert themselves at unexpectedly high rates into brain cells’ nuclear genomes. What’s more, these insertions might be associated with life ...

Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts. PLOS Biology , 2024; 22 (8): e3002723 DOI: 10.1371/journal.pbio.3002723 Cite ...

As direct descendants of ancient bacteria, mitochondria have always been a little alien. Now a study shows that mitochondria are possibly even stranger than we thought. The study, titled "Somatic ...

Mitochondrial disease refers to a group of conditions that affect how mitochondria work. While there is no cure for mitochondrial disease, supportive care can help prevent life threatening ...

One mitochondrial sample was even complete enough to meet the requirements for the federal missing-persons database. Anna Lewis, a Harvard researcher who studies the ethical, legal and social ...

One mitochondrial sample was even complete enough to meet the requirements for the federal missing persons database. They also found key mutations shown to carry a higher risk of diabetes ...

Healthy mitochondria, those tiny cellular structures high school biology teachers often tout as “the powerhouses of the cell,” are a necessity for producing energy in the body—but new ...

SCENT uses single-cell multimodal data (e.g., 10X Multiome RNA/ATAC) and links ATAC-seq peaks (putative enhancers) to their target genes by modeling association between chromatin accessibility and ...