Scientists found a compound that appears to counter common mutations behind POLG-related diseases, rare conditions that harm mitochondrial DNA. Comments ( 0 ) ( ) ...

The researchers selected ischemic heart disease (IHD) as their test model, as this condition creates high energy demands where mitochondria must generate substantial energy to maintain normal cardiac ...

releasing their products into the bloodstream for the benefit of cells that cannot generate enough mitochondria by themselves. Certainly, blood contains huge numbers of free-floating mitochondria ...

Virginia Tech neuroscientists have uncovered a mitochondrial process that supports the brain cells critical for learning, memory, and social recognition. Led by Shannon Farris, assistant professor ...

An emerging area of research is the evolutionarily conserved transfer of mitochondria between cells. Yet researchers have lacked unique and universally accepted terms and practices to describe such ...

Most of us remember two things from high school biology: that mitochondria are the powerhouses of cells and that we inherit stable sets of chromosomes from our two parents. Both truisms are only ...

Mitochondria, critical for cellular energy ... through disulfide bonds, create a diblock copolymer (HAssLG). Doxorubicin (DOX)-loaded HAssLG nanoparticles prepared through dialysis exhibit a spherical ...

Bits of genes that typically reside in mitochondria insert themselves at unexpectedly high rates into brain cells’ nuclear genomes. What’s more, these insertions might be associated with life ...

Researchers at the Hospital for Sick Children (SickKids) report that mitochondria depend on a newly discovered recycling mechanism. Their research demonstrates mitochondria can recycle a localized ...

Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts. PLOS Biology , 2024; 22 (8): e3002723 DOI: 10.1371/journal.pbio.3002723 Cite ...

Extracellular vesicles are nanoparticles released by all cell ... we found that those two processes are controlled by two enzymes that generate ceramide at the plasma membrane," said Zainuddin ...

The nanoparticle is made of a biodegradable polymer that is loaded with two prodrugs that target cancer cells' mitochondrial DNA, according to a May 6 article on the university's website.