Researchers at Duke University Medical Center and Wake Forest University School of Medicine have identified ALDH4A1, a ...

Mitochondrial diseases affect approximately 1 in 5,000 people worldwide, causing debilitating symptoms ranging from muscle weakness to stroke-like episodes. Some of these conditions result from ...

Researchers have revealed critical insights into how impaired mitochondrial dynamics and quality control mechanisms in skeletal muscle influence insulin sensitivity in patients with Type 2 Diabetes, ...

Researchers have revealed critical insights into how impaired mitochondrial dynamics and quality control mechanisms in ...

How well our brain functions depends heavily on the performance of our nerve cells. That is why they are regularly checked for their proper function -- defective cell components are marked, disposed ...

The human body undergoes numerous changes throughout life, with many significant transitions occurring during the decade of ...

The study highlights ALDH4A1’s role as a tumor suppressor by preventing a harmful shift in how cells produce energy.

The study, titled "Deubiquitinating Enzymes Regulate Skeletal Muscle Mitochondrial Quality Control and Insulin Sensitivity in Patients with Type 2 Diabetes," was recently published in the Journal ...