The human genome is broadly classified into the genome residing in the cell nucleus (nuclear DNA) and the genome residing in ...

Mitochondria play a central role in energy metabolism and overall health. In obesity and its comorbidities, mitochondrial ...

Patients with rare mitochondrial diseases already face a host of serious health issues, from muscle weakness to neurological ...

A discovery at The Jackson Laboratory reveals how dysfunctional mitochondria put the immune system on overdrive, leading to ...

The study suggests that reduced mitochondrial metabolism can contribute to body fat accumulation and diminished insulin ...

People's immune systems deteriorate as they age, making cancer therapies that rely on immune cells difficult to implement. In ...

Age-related decline in the immune system can have a measurable impact on CAR-T cell therapy — one of the most advanced forms ...

Mitochondria are cytoplasmic organelles found in most eukaryotic cells. They are formed from ... Here authors show, in a mouse model of polymerase gamma (Polg)-related mitochondrial disease ...

As people age, their immune systems become less efficient, posing a challenge for cancer therapies that rely on harnessing immune cells. In a new ...

Patients with rare mitochondrial diseases already face a host of serious health issues, from muscle weakness to neurological ...