In all eukaryotes, a microtubule-based structure known as the spindle is responsible for accurate chromosome segregation during cell division. Spindle assembly and function require localized ...

Initiation of mitosis is accompanied by chromosome condensation and nuclear envelope breakdown; this coincides with disassembly of interphase microtubule and actin arrays and assembly of the ...

Mutation of Lis1, a key dynein regulator, can lead to the rare mental developmental disorder lissencephaly, or “smooth brain, ...

thus increasing the free energy barrier that needs to be overcome to form a straight microtubule lattice. Electron Tomography Confirms Predicted Structural Differences at the Ends of Growing and ...

This step of actin assembly/disassembly is followed by the addition of tubulin to measure again centrosome nucleation capacity. The amount of microtubule per centrosome is compared between the first ...

Department of Chemistry, Binghamton University, State University of New York, Binghamton, New York 13902, Department of Chemistry, M/C 0212, Virginia Polytechnic Institute and State University, ...

Both impaired actin reorganization and attenuated microtubule filament formation inhibit cancer cell migration and invasion, thereby preventing metastasis. On the other hand, failure of spindle ...

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During ...

The assembly prioritized Indigenous voices, recommending opportunities for land use and cultural preservation. The final report will be presented to the City Council for review and potential action.

Stellantis outlined its production schedule through July for Windsor Assembly Plant to its suppliers and Unifor Local 444 Monday and confirmed to the Star it still plans on making the facility a ...

The National Assembly has urged the Supreme Court to dismiss the suit filed by 11 Peoples Democratic Party governors challenging the declaration of a state of emergency in Rivers State.

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...