The guanosine tri-phosphatase Ran stimulates assembly of microtubule spindles. However, it is not known what aspects of the microtubule cytoskeleton are subject to regulation by Ran in mitosis ...

Many fundamental processes of life, and their synthetic counterparts in nanotechnology, are based on the autonomous assembly ...

"Nucleotide-dependent bending flexibility of tubulin regulates microtubule assembly," by Hong-Wei Wang and Eva Nogales, appears in the 16 June 2005 issue of Nature.

Researchers led by Dr. Jens Lüders at IRB Barcelona have discovered a key role played by the ch-TOG protein in the initiation of microtubule assembly during the interphase stage of the cell cycle ...

Berkeley Lab researchers have produced images of microtubule assembly and disassembly at the unprecedented resolution of 5 angstroms, providing new insight into the success of the anti-cancer drug ...

Microtubule Nucleation: CDK5RAP2 activates γTuRC, enabling it to efficiently initiate microtubule assembly. Cryo-EM Imaging: Advanced imaging techniques revealed structural changes in γTuRC triggered ...

Inside every cell, a network of tiny filaments, called the microtubule cytoskeleton, helps maintain the cell's shape, allows it to divide, and transports vital materials from one part of the cell ...

However, the precise rules dictating whether a microtubule grows or shrinks have long remained a mystery due to the complexity and miniature size of their ends.

Visualizing 'unfurling' microtubule growth Date: November 13, 2018 Source: University of California - Davis Summary: Living cells depend absolutely on microtubules that form a scaffolding for ...

The research team used magic-angle-spinning nuclear magnetic resonance spectrometry (NMR) in the Department of Chemistry and Biochemistry at UD to unveil the structure of the CAP-Gly protein ...

This article presents the various tools available to explore and understand the Tubulin Code via the function and dynamics of microtubules.