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Renal biopsy remains the gold standard for diagnosis, with the pathognomonic finding of predominant or codominant mesangial IgA deposits on immunofluorescence.
However, pSS can also affect the kidneys, most commonly involving the kidney interstitium. Recent studies have demonstrated that some membranous nephropathy (MN) cases are associated with Sjögren’s ...
Following its lead Graves’ disease programme, Merida plans to pursue candidates for food allergies and primary membranous nephropathy, a rare autoimmune kidney disorder. Merida will be led by CEO Adam ...
Therefore, I will focus on the most common causes of nephrotic syndrome — minimal change disease, focal segmental glomerulosclerosis (FSGS), and membranous nephropathy. Minimal Change Disease ...
Other disclosed Merida programs are in preclinical development for primary membranous nephropathy, which is a chronic inflammatory kidney disease, and food allergies mediated by immunoglobulin E ...
The company currently has programs targeting Graves' disease, allergy and primary membranous nephropathy, a chronic autoimmune disease that affects the kidneys. "We are driven by the opportunity ...
Merida is also working on a treatment for a chronic inflammatory kidney disease called primary membranous nephropathy. “At the heart of Merida is understanding the mechanisms behind antibody ...
Merida’s Graves’ disease program is currently in the IND-enabling stage. The biotech is also working on IgE-mediated allergic diseases and primary membranous nephropathy, both of which are still ...