In primary cells, ORC1 was dispensable in the mouse liver for endo-reduplication, but this could be explained by the ORC1 homolog, CDC6, substituting for ORC1 to restore functional ORC. Here, we have ...

While the task measured cognitive flexibility in mice, it remains unknown whether the effects would translate to humans or to other types of cognitive flexibility beyond reversal learning. The study ...

1997; Peier et al., 2002). In particular, genetically modified knockout (KO) mice models have emerged as powerful tools to explore TRP channel functions in cardiac tissue, allowing for precise ...

The work presented is important for our understanding of the development of the cardiac conduction system and its regulation by T-box transcription factors. The conclusions are supported by convincing ...