In the retina, age-related macular degeneration (AMD ... circulating lymphocytes and monocytes/macrophages and mast cells. Stimulation of monocytes can lead to interleukin secretion and ...

Wet age-related macular degeneration (AMD ... study shows for the first time that the release of substances from mast cells may be a causal factor in this type of eye pathology, and inhibitors ...

Stanford University School of Medicine scientists have definitively linked mast cells, a class of cells ... bone-on-bone contact and degeneration in the affected joints. But the new study shows ...

Certain immune cells backstab their cellular coworkers during allergic reactions. Mast cells, the security patrols of the immune system, can trigger allergic inflammation when they run into ...

A rare set of immune diseases called clonal mast cell activation disorders (cMCADs) may be associated with strong immunity to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 ...

A potential new treatment for mast cell cancers reduces the number of mast cells by "mutating" the messenger RNA (mRNA) before it can deliver instructions for manufacturing the gene responsible ...

Reference: Mcharg S, Booth L, Perveen R, et al. Mast cell infiltration of the choroid and protease release are early events in age-related macular degeneration associated with genetic risk at both ...

The paper Mast cell infiltration of the choroid and protease release are early events in age-related 2 macular degeneration associated with genetic risk at both chromosome 1q32 and 10q26 is published ...