during DNA damage bypass. In addition to a catalytic function across minor groove DNA lesions, Polκ stimulates Polζ-mediated extension past various DNA lesions. DNA polymerase ζ (Pol ζ ...

According to this approach, small minor groove binding molecules have been designed to bind the DNA sequence specifically and thereby downregulate genes. Because of their lack of druglikeness, we plan ...

In the major pathway of homologous DNA recombination in prokaryotic cells ... Each arm, with B-form DNA, in the Holliday junction is predominantly recognized in the minor groove through hydrogen bonds ...

Figure 6. Overlapping DNA contacts. Loop L1 of IRF‐3A inserts into the minor groove opposite c‐Jun, and loop L1 from IRF‐3B inserts opposite to helix α3 of IRF‐3A. What stabilizes the 2 bp spacing of ...

A unique feature of HR is that it repairs the damage to the DNA in a highly accurate way. In eukaryotic cells (those with a ...

Five months after cutting his right hand preparing a Christmas dinner, world number one Scottie Scheffler has himself on the verge of a third major title at the PGA Championship. The 28-year-old ...

Five months after cutting his right hand preparing a Christmas dinner, world number one Scottie Scheffler has himself on the verge of a third major title at the PGA Championship. The 28-year-old ...