Oncolytic adenovirus was engineered for the forced ectopic delivery of peptide-MHC ligand of T cell receptors (TCRs) to ...
MHC-I upregulation by macbecin II in the solid tumors potentiates the effect of active immunotherapy
We aimed to restore MHC-I expression on the surface of solid tumors including breast cancer and melanoma cells to regain sensitivity to immunotherapy and suppress metastatic progression. We screened a ...
Whole blood was stained with the direct addition of 1 μL of PE-conjugated H-2K(b) VNFNFNGL Tetramer (1:100, NIH Tetramer Core Facility ... AB_493696), 0.5 μL of MHC II eFluor 450 (clone M5/115.15.2, ...
Since TP conjugation is restricted to peptides, this requires the identification and characterization of immunogenic T cell epitopes and their corresponding MHC molecules. The direct delivery of ...
Proteins change their conformations as part of their biological functions, for example, when binding another molecule (ligand). Two pathways are conceivable: Either the ligand binds preferentially to ...
Choice of assay should be made with care and attention be paid to dynamic range, especially around or below the cut-off for normal ranges. Preferably, an assay with a calibration curve should be ...
Department of Physics, Faculty of Science at Çanakkale Onsekiz Mart University, Çanakkale 17100, Turkey ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback