Endogenous intracellular allosteric modulators of GPCRs remain largely unexplored, with limited binding and phenotype data available. This gap arises from the lack of robust computational methods for ...

PPARα activators induce fatty acid oxidation in the liver, thereby improving lipid and carbohydrate metabolism in obese mice. In this study, the dietary cis-carotenoids bixin and norbixin, which are ...

Second, by recruitment of intestinal lymphatic drug transport (and reduced first-pass metabolism ... long-chain and unsaturated lipids) recruit endogenous and exogenous lipid transport and ...

Potential topics include, but are not limited to: •Biological function in the new compounds releasing H 2 S, polysulfide and SO 2 •New methods for detection of endogenous and exogenous H 2 S •Advances ...

In support of this hypothesis, several recent studies have shown that reduction of toxic lipids is associated with improved metabolism and function of the heart. The role of the metabolic syndrome was ...

To study isoprenoid and lipid metabolism in grape skin chloroplasts, metabolites of enriched organelle fractions were analyzed by high-performance liquid chromatography-high-resolution mass ...

surrounded by lipid globules and bilayer membranes that are susceptible to lipid metabolism-related changes with age. Photo credit: Google Image Fx/UC San Diego Health Sciences. Our immune systems ...

CYP2E1 is involved in the metabolism of endogenous ketones and also participates in the metabolism of gluconeogenesis through ketone bodies. Ketone bodies can be efficient fuel in special disease ...