Building on the work of Nobel Prize-winning chemist Linus Pauling, Ingram compared the hemoglobin of a normal red blood cell to the hemoglobin of a sickle cell. Using a technique that he developed ...

In 1949, a team led by chemist Linus Pauling placed hemoglobin solutions from people with a disabling form of anemia and from healthy volunteers in an electric field, and found that the two samples ...

Its cause, abnormal hemoglobin, was discovered in 1949 by chemist Linus Pauling. Hemoglobin is the protein in red blood cells that carries oxygen throughout the body. Pauling showed that ...

chemist Linus Pauling published a paper in the journal Science describing how the oxygen-carrying protein hemoglobin is different in people with sickle cell, declaring the malady the first ...

In a study that challenges currently held views, researchers unravel the molecular mechanism whereby sickle cell hemoglobin confers ... (mutation), in 1949 by Linus Pauling (two-times Nobel ...

this disease caught the attention of Linus Pauling. Since red blood cells contain large amounts of hemoglobin, Pauling thought it would be worthwhile to examine the properties of hemoglobin ...

when the chemist Linus Pauling, who would win two Nobels, measured an atomic charge difference between normal and sickled hemoglobin, leading him to dub sickle-cell the “first molecular disease ...

The answer came, in part, thanks to a massive physical model of the protein deoxyhemoglobin (hemoglobin not yet bonded to oxygen ... led Murayama to a postdoc at Caltech working with Linus Pauling, ...

In 1949, the eminent biochemist Linus Pauling published a paper linking the illness to hemoglobin, an oxygen-carrying protein in the blood. Among sufferers, the structure was abnormal. Pauling ...