2004). Also, whereas bacterial chromosomes are circular, eukaryotic chromosomes are linear. During circular DNA replication, the excised primer is readily replaced by nucleotides, leaving no gap ...

Donald Coffey, a longtime professor at Johns Hopkins University, discovered the nuclear matrix within cells and its role in DNA replication. Telomeres are repetitive, noncoding sequences that cap the ...

A research team led by Prof. GAN Haiyun from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences has uncovered a reciprocal regulatory relationship between ecDNA ...