Whether antiretroviral therapy (ART) is always completely suppressive, or HIV might continue to replicate at low levels despite ART in some people with HIV (PWH), is still debated. Here, we ...

By Pooja Toshniwal PahariaA recent study in Nature Plants examined the genetic regulation of endosymbiotic gene transfer (EGT) in plants. Researchers found that deoxyribonucleic acid (DNA) ...

Drs Ursula A. Matulonis and Joyce F. Liu discuss targeting DNA damage and repair and replication stress in endometrial cancer.

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

Using cultured human cells with genome-edited TEFM knockout, the team studied the effects of deletion of TEFM on mtDNA replication. By knocking out TEFM, they observed a notable reduction in mtDNA ...

News Release 6-Dec-2024 New model for replication of BKPyV virus, a major cause of kidney transplant failure There are no effective antivirals against BK polyomavirus in transplanted kidneys.

The fact that TAg was expressed after DNA replication suggested it was expressed too late to be responsible for driving cells into replicating their DNA. Sunnie Thompson, Ph.D. TAg expression and ...

Professor Morris added: "The finding that cellular nucleases and helicases can stop replication of certain sections of DNA was a surprise – it shows that cells closely co-ordinate their toolkit ...

An article by UAB professor Joan-Ramon Daban analyzes in depth the physical problems associated with DNA packaging that have ...

Enzymatic DNA synthesis promises to resolve many of the difficulties encountered with chemical DNA synthesis. For example, it promises to sustainably produce more complex templates at either bench ...

Double trouble at chromosome ends Date: February 28, 2024 Source: Rockefeller University Summary: New findings suggest the end-replication problem, an old standby of biology textbooks, is twice as ...