A key feature of cancer cells is their forced proliferation, which causes a hasty uncontrolled start of DNA replication. To date, however, little is known about the mechanisms that control the start ...

Mitochondrial diseases, arising from mutations in mitochondrial DNA (mtDNA), are a diverse group of disorders that lead to severe conditions. Expression of mtDNA is a prerequisite for ATP production ...

These essential enzymes maintain genome integrity and play a vital role in DNA replication and repair across all living organisms. By forming phosphodiester bonds, it ensures the seamless connection ...

The team's o3-mini model matches human judgment with 83 percent accuracy ... Basic reasoning capabilities don't improve paper replication success. Claude 3.5 Sonnet leads without specialized reasoning ...

Donald Coffey, a longtime professor at Johns Hopkins University, discovered the nuclear matrix within cells and its role in DNA replication. Telomeres are repetitive, noncoding sequences that cap the ...