Ligand Pharmaceuticals Incorporated ... a dual endothelin and angiotensin II receptor antagonist for immunoglobulin A nephropathy; Ohtuvayre for respiratory disease; PNEUMOSIL, a pneumococcal ...

Mapping an antibody’s epitope, where it binds a target, can now be done in three dimensions, which optimizes the selection of application-specific antibodies.

Failure to start resolution mechanisms might be due to limited availability of ligand-receptor interactions, a shortfall which might be corrected by exogenous delivery of FPR2 agonists. There are at ...

NK cells do not express polymorphic clonotypic receptors and utilize inhibitory receptors (killer immunoglobulin-like receptor and Ly49) to develop, mature, and recognize “self” from “non-self.” The ...

Upregulation of the cytokines CXCL1/2/3 occurred through direct binding of HEYL to their promoter sequences ... induced by HEYL using a small molecule inhibitor of the CXCl1/2/3 receptor, CXCR2, in ...