Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

Lentiviral vectors (LVVs ... has its own peculiarities and associated complexity when compared with other vector types, especially because of the intrinsic characteristics of the vectors ...