Greater numbers of circulating stem cells increase the efficacy of in vivo gene therapy techniques, potentially reducing the price tag of lifesaving treatments.

Find more information on the Altmetric Attention Score and how the score is calculated. The field of mammalian synthetic biology is expanding quickly, and technologies for engineering large synthetic ...

AGC Biologics will provide lentiviral vector (LVV) material using its proprietary ProntoLVV™ platform to prepare these therapies for CTA / IND submissions. Quell is working to create ...

Compared with the traditional VSV-G pseudotyped lentiviral vector, MxV-G pseudotyped vector not only enhances viral titer and transduction efficiency but also enables generated CAR-T cells to more ...

Maximilian Klimpel planned and executed experiments for lentivirus productions. Christin Obert, Silke Wissing and Monica Terrao developed the analytical technologies for determination of ...

Get Instant Summarized Text (Gist) Generative AI has been used to design synthetic DNA regulatory sequences that precisely control gene expression in healthy mammalian cells. These AI-generated ...

"LICONN brings us a step closer to assembling the puzzle pieces of the mammalian brain and better understanding its functioning both in health and disease," Danzl concludes.

Transduction involves using a non-replicating virus, like a modified lentivirus, to bring genetic material into the cell; transfection involves introducing genetic material using a non-viral method.