Our results establish a role for METTL3 and 6mA in promoting genome stability in mammalian cells ... cDNAs were delivered by retroviral or lentiviral transduction after packaging in HEK 293T cells.

Lentiviral transduction is a popular and powerful gene delivery method for downstream applications such as cell line generation, therapeutic model generation and CAR-T research. However, current ...

Professor Amrolia selected ViroCell to manufacture the lentiviral vector for this novel CAR T-cell therapy based on its track record for delivering high quality vector. Through this relationship ...

Baculovirus transduction is a gene transfer method that uses a moth cell virus for mammalian cells in culture, which results in a high-level prolonged expression. Here we demonstrate that ...

Apr. 4, 2025 — New research shows how small shifts in the molecular makeup of a virus can profoundly alter its fate. These shifts could turn a deadly pathogen into ... Apr. 2, 2025 — A new ...

1B and EV1C). Our pipeline also identified multiprotein complexes involved in signal transduction, specifically the catalytic and one regulatory subunits of protein phosphatase 2 (PPP2CA and PPP2R1A, ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Neoantigen vaccine is a promising breakthrough ...

School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, the University of Dublin, College Green, Dublin 2 D02 PN40, Ireland Trinity Translational Medicine Institute, Trinity College ...