If preclinical findings were translated into the clinic, they could shorten the CAR-T generation lead time from two weeks to ...

Using CRISPR-Cas9 edited iPSC-derived MN models ... For MN survival experiments, lentiviral SYN1-GFP (PZ196, Addgene) was added to MNs in suspension prior to seeding onto ImageLock 96 well plates ...

To discover factors in repair of genomic uracil, we performed a CRISPR knockout screen in the presence ... cDNAs were delivered by retroviral or lentiviral transduction after packaging in HEK 293T ...

Lentiviral transduction is a popular and powerful gene delivery method for downstream applications such as cell line generation, therapeutic model generation and CAR-T research. However, current ...

A team of CiRA researchers has uncovered the crucial role of EIF3D—a protein translational regulator—in primed pluripotency.

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...

A Peninsula biotech company raised $68 million from investors — including a venture philanthropy fund started by Lululemon Athletica founder Chip Wilson — to push a next-generation CRISPR drug ...