In this paper, we show that the SOS-mediated induction of lambda lysogens into lytic cycle allows the direct, positive selection of phages encoding improved prodrug-activating enzymes.

The lytic and lysogenic cycles are the two main phases of a virus’ infective lifecycle and route to replication. The lytic cycle, or virulent infection, involves a virus taking control of a host cell ...

Lytic vs lysogenic cycles: What's the difference? The lytic and lysogenic cycles are the two main phases of a virus’ infective lifecycle and route to replication. The lytic cycle, or virulent ...

In the lytic cycle, full copies of the virus are made inside of a cell, say an E. coli cell. When the phage-infected cell becomes full of the replicating viruses, it bursts open and is destroyed.

Phage therapy uses viruses to target specific bacteria and eliminate them through biological mechanisms such as the lytic cycle.

Temperate bacteriophages display a lysogenic life cycle, which requires them to integrate their viral genome into the bacterial chromosome.

Researchers analyze prophages of the LF82 strain of adherent-invasive Escherichia coli to better understand their behavior in vitro and within macrophages.

A 45-year-old woman was evaluated in the rheumatology clinic because of possible IgG4-related disease. She had polyclonal hypergammaglobulinemia, as well as kidney and bone lesions. A diagnosis was ...