It literally walks along the surface of the microtubules, lurching forward step by step. Kinesin gets its energy from a molecule called adenosine triphosphate (ATP). Every step forward requires ...

Kinesin is a vital player in transporting cargo, like neurotransmitter-filled vesicles, along the microtubule rails that span our cells. Fueled by the splitting of ATP, kinesin moves by “stepping” ...

answered a long-standing question of head coordination in kinesin. They found that fluorescent ADP produced by the hydrolysis of fluorescently labeled ATP nucleotides is not immediately released ...

kinesin-1, and a microtubule-containing motility solution. After washing off unbound microtubules, the fiber was immersed in the analyte solution. Motility was powered by ATP, while analyte ...

An active nematic suspension composed of microtubule bundles driven by ATP-powered kinesin clusters continuously flows in a turbulent-like manner and produces motile topological defects. By confining ...

Additionally, Boundless is on track to nominate a candidate for its novel Kinesin program by mid-2025 and plans to submit an IND application in the first half of 2026. As of March 31, 2025 ...

and cell biological mechanisms of the cytoskeletal molecular motors dynein and kinesin. The group studies these molecular machines in two ways: 1) at the level of individual motors to better ...