We found that microtubule deformation significantly slowed kinesin-driven transport, whereas we previously reported dynein-driven transport was rather robust. Such dualistic modulation of ...

Although muscles are an obvious example of motor proteins in action, even something as fundamental as cell division (mitosis) involves motor proteins, specifically kinesin microtubule motors.

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. During mitosis, motor proteins and microtubule ...

This contrasts with dynein, which is another member of the of cytoskeletal motor protein family that transports its cargo towards the minus end of the microtubule. Structurally, kinesin exists as ...

In most organisms, these Pac-man-like molecules are a group of proteins from the kinesin-13 subfamily that lead to microtubule shortening. Interestingly, during cell division in fission yeast ...

Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai, India Kinesins, the microtubule-dependent mechanochemical enzymes, power a variety of intracellular movements.

"Our publication details how GSK3β attaches a molecular tag to kinesin 1 motors, which causes the motors to stop without detaching from microtubule tracks. We are super excited, since now we know ...

They found that kinesin movement is slowed down when the microtubule is bent. Using high-speed atomic force microscopy, which allows for the observation of dynamic processes at the atomic level ...

They found that kinesin movement is slowed down when the microtubule is bent. Using high-speed atomic force microscopy, which allows for the observation of dynamic processes at the atomic level ...

Here, we describe a regulatory mechanism involving direct binding between tail and motor domains and its fundamental role in microtubule sliding. Kinesin-5 tails decrease microtubule-stimulated ...

Islands fused when they met along the microtubule length. Their formation required a minimum ... Jochen Krattenmacher at the Czech Academy of Sciences found that while the kinesin-1 motor could easily ...

This self-assembly was made possible by the binding of complementary DNA strands attached to each component. The team then designed a "kinesin linker" which is made of four kinesin motor proteins ...