In 1992, graduate student Yasumasa Ishida discovered PD-1, marking the beginning of a journey that would make this molecule a ...

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During ...

Researchers have captured a time-resolved video of a protein interaction essential to healthy brain development.

Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA ...

UNIVERSITY PARK, Pa. — Penn State University Libraries presented its eighth annual Undergraduate Research Award: Excellence ...

Abstract: The cytoskeletal motor protein kinesin-1 has been successfully used for many nanotechnological ... the total number of microtubules is limited and detachment at the structure walls causes ...

Because kinesin-1 motors processively move along individual protofilaments ... This mapping allows the correlation of motor-filament interactions with the microtubule fine-structure. With the ...

Give your thesis, definition, or takeaway up top, then expand on it. Signal structure with phrasing like “Step 1,” “In summary,” “Key takeaway,” “Most common mistake,” and “To ...

38362). Our recent work in this area employing computational structure prediction and electron microscopy has led to the development of a new model for the autoregulation of the kinesin-1 holoenzyme ...

Here, we combine crosslinking mass spectrometry (XL-MS), electron microscopy (EM), and AlphaFold structure prediction to determine the architecture of the full-length autoinhibited kinesin-1 homodimer ...

Kinesin‐driven intracellular transport ... corresponding to a 1:1 stoichiometric ratio of the KIF3A/B dimer and KAP3 (Fig 1B). Cartoon representation of the structure of the KIF3/KAP3 complex (upper ...