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The study, published in Molecular Neurodegeneration, examined age-related changes in genes and proteins of the retinas of nine strains of mice, mimicking the genetic variability found in humans.
In two new papers, researchers from The Jackson Laboratory (JAX) report the successful use of two approaches -- gene therapy and bone marrow transplantation – to alleviate symptoms of ...
Former NWA Worlds Heavyweight Champion and multi-time NWA National Heavyweight champion Jax Dane passed away at 48 years old on Wednesday, December 25.
Summary These Gba1 knock-in (KI) mice carry a leucine to proline mutation (L444P) in exon 10 of the mouse Gba1 (glucosidase [GCase], beta, acid 1) gene, resulting in Gba deficiency (Ginns et al., 2014 ...
Researchers are working to create the first strain of mice that's genetically susceptible to late-onset Alzheimer's, with potentially transformative implications for dementia research.
Mice don't get Alzheimer's - and while that's good news for mice, it's a big problem for biomedical researchers seeking to understand the disease and test new treatments.
The new protocol coaxes mouse stem cells to develop across multiple strains of mice, not just strain 129. This enables researchers to identify which strain best resemebles cells in different human ...
The CAR T cells were detectable in the spleens and livers of treated mice 12 months after the initial single infusion. The treatment also appeared to prevent metabolic decline as the mice aged.
The best way to think about the retirement age chart is as a line in the sand. This line in the sand, which is specific to your birth year, provides a baseline that determines if you'll receive ...
13,000 Strains of research mice offered by Mount Desert Island’s Jackson Laboratory for Mammalian Genetics. Founded in Bar Harbor, in 1929, the lab sold 10 strains in its first commercial catalog (for ...
It had been approved by the Ethics Committee of the State Ministry of Agriculture, Nutrition and Forestry, State of Hessen, Germany (V54-19c20/15-FU-1192 and V54-19c20/15-FU-1213). 8-10-week-old mice ...
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