Legendary Rams wideout Isaac Bruce capped his Hall of Fame career by playing two seasons with the 49ers, proving he was a productive veteran. Kevin Greene recorded 10.5 sacks during his lone ...

Just a week ago, it seemed like Isaac Guerendo might not make the 49ers' 53-man roster. Now, it seems like he'll be their primary kick returner. That's how much can change in a few days.

Rookie running back Isaac Guerendo was carted off the field less than two minutes into the first quarter during the 49ers’ season finale in Arizona against the Cardinals with a leg injury.