With advances in stem cell technology ... Researchers are working on ways to automate and scale up organoid production, but cost and efficiency remain barriers. Compared to other digestive organs, the ...

Organoids—self-organizing 3D structures derived from stem cells—have brought researchers ... in the journal Cell Organoid, a comprehensive review from researchers at Peking University and ...

By comparing young and aged mouse intestinal tissues, the researchers uncovered critical insights into the interplay between these signaling pathways in supporting stem cell maintenance over time.

“With such an organoid ... digestive enzymes and the endocrine cells produced hormones.” Using these organoids, the researchers discovered new information about how the pancreas develops ...

Intestinal tuft cells ... in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation damage, and contribute to the epithelium’s regeneration. That is what ...

researchers have now created a living biobank of organoids derived from adult stem cells in the gut tissue of Crohn’s disease patients—CD patient-derived organoid cultures (PDOs)—which more ...

The different cell ... regulate digestive processes, such as nutrient absorption, appetite and glucose metabolism. In this study, researchers from the Organoid group investigated how stem cells ...

Rather, stem cells choose their identity first and only then move to their appropriate position. These discoveries were made using intestinal ... 3D movie of a growing organoid for about 60 ...

Here we discuss current advances made to help create and maintain organoid cultures. In 2009, Prof. Toshiro Sato and Hans clever achieved the in vitro expansion of the adult stem cells from mouse ...