Stem-cell derived organoids provide the perfect mixture of cells to rebuild damaged intestines.

A team of CiRA researchers has uncovered the crucial role of EIF3D—a protein translational regulator—in primed pluripotency.

Drug-Delivering Aptamers Target Leukemia Stem Cells for One-Two Knockout Punch Apr. 3, 2025 — Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the ...

Organoids are made to model human organs and are promising for research and therapy, but there are limitations in their growth and function. A recent study found that placenta-derived IL1 under ...

Organoids are small-scale models that mimic human organs. These models could help scientists understand diseases and test treatments, and potentially aid in regenerative therapeutic methods.

A human mature adipose tissue organoid containing adipocytes, fibroblast, and endo-thelial cells: Red = Actin, Green = Bodipy (specific for adipocytes) Blue = DAPI (nuclei), Pink = CD31 ...

It is unclear which intestinal epithelial cell-derived cytokines can precisely regulate intestinal stem cell (ISC) commitment toward specific mature cells. Here, authors identify an epithelial ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Recent IVG breakthroughs bring gene-edited human embryos closer, with CRISPR-Cas9 making heritable gene editing a reality ...