In this valuable study, the authors demonstrate that TCF7L2 plays a role in the pathogenesis of cachexia in a mouse model of GI cancer. The results are solid, although future studies will need further ...

innate immune cells), muscular and neurological elements Intestinal permeability is defined as a functional feature of the intestinal barrier at given sites, measurable by analyzing flux rates ...

More than 280,000 people in Germany have multiple sclerosis (MS) and approximately 15,000 new cases are diagnosed each year.

Researchers at the Tohoku University Graduate School of Medicine have uncovered a key primary step in the hepatic ERK pathway ...

Gut organoids mimic the stomach, small intestine, and colon in 3D. Learn how these lab-grown models are advancing digestive ...

When Treg cells are produced, they are trained to recognize specific peptides, including self-peptides from the body. When dendritic cells present a self-peptide, the peacekeeper Treg cells trained to ...

Apr. 25, 2025 — Chimpanzee naive pluripotent stem cells (PSCs) can now be grown in cellular cultures, reveals a recent study. They successfully created chimpanzee early embryo models ...

Moreover, these results suggest that intestinal stem cell-intrinsic DNA methylation patterns establish and maintain regional gut specification and are involved in early epithelial development and ...

Like other essential oils discussed above, the antioxidant capabilities of rose essential oil may protect skin cells from free radicals and sun damage, which both contribute to skin aging.

Metabolomic, transcriptomic, and scRNA-analyses revealed that EGFR deletion in KRAS-mutant organoids reduced their phenotypic heterogeneity and activated a distinct cancer-stem-cell/WNT signature ...

Astrocytes, the most numerous glial cells in the brain, play an important role in preserving normal neural functions and mediating the pathogenesis of neurological disorders. Recent studies have shown ...