In the realm of colorectal cancer treatments beyond surgery and radiation, one key question gained prominence in recent years ...

Chronic inflammatory bowel disease is challenging to treat and carries a risk of complications, including the development of ...

Dual MAPK inhibition (dMAPKi) as an effective therapeutic strategy for class II BRAF mutant (mt) metastatic melanoma (MM). This is an ASCO Meeting Abstract from the 2018 ASCO Annual Meeting I. This ...

A new report by FutureWise Research highlights a powerful trend in modern medicine: as awareness and innovation rise, hope ...

CONTEXT: Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor. Cellular proliferation and apoptosis is gaining importance for predicting prognosis in several cancers. OBJECTIVE: ...

The best way to decrease your risk of serious cancer is to get tested for it. Because colon and rectum are both parts of the large intestine, screening for cancer in these areas is similar. These ...

In 1997, a Johns Hopkins research team found an inherited genetic mutation called APC I1307K. Adenomatous polyposis coli (APC) is a gene that suppresses tumor growth. If the APC gene is defective, it ...

The classification and nomenclature are not well established and knowledge acquired in neuroendocrine neoplasms of lungs and certain gastrointestinal sites ... ("neuroendocrine" [All Fields] OR ...

The usual carcinoid is seen at autopsy as a small ... is occasionally seen and is the usual way that such tumors cause intestinal obstruction. Intussusception was caused by benign lesions in ...

However, contradictory roles for TCF7L2 in colon tumors have arisen from several studies using different strategies to target the gene (6–10). TCF7L2’s role in small intestine tumors is poorly ...