with efficacy depending on the high expression of interleukin-10 receptor (IL-10R) on CD8 + TRM cells. To investigate the ...

Explore the promising results of haematopoietic stem cell transplantation as a treatment for early-onset inflammatory bowel ...

The authors' work 3, however, primarily highlights the role of memory B-cell IL-10 in downregulating the active inflammatory response in EAE (that is, disease remission), less so the role of B ...

The authors recount their discovery of how pathogen-induced interleukin 12 production leads to T H 1 T cell polarization. Simultaneously they discovered the suppressive cytokine interleukin 10 ...

such as interleukin-10 (IL-10) MESA and transforming growth factor beta (TGFb) MESA. This suggests that additional factors, ...

with efficacy depending on the high expression of interleukin-10 receptor on the T cells and neutrophils in tumors only. "Our findings illuminate a crucial, yet previously unresolved mechanism in ...

Summary: Tocilizumab is a novel monoclonal antibody that competitively inhibits the binding of interleukin-6 (IL-6) to its receptor (IL-6R). Inhibiting the entire receptor complex prevents IL-6 ...