3–6 Mice that are deficient in either interleukin-10 or interleukin-10 receptor 2 have been shown to have severe enterocolitis, 26–28 a finding that underscores the pivotal role of interleukin ...

Interleukin (IL)-10 is an important immunoregulatory cytokine that mediates its effects via a transmembrane receptor complex consisting of two different chains, IL-10R1 and IL-10R2. While IL-10R2 ...

Summary: Tocilizumab is a novel monoclonal antibody that competitively inhibits the binding of interleukin-6 (IL-6) to its receptor (IL-6R). Inhibiting the entire receptor complex prevents IL-6 ...

R denotes receptor. Interleukin-23 can expand a population ... which resemble regulatory T cells and produce interleukin-10 and interferon-γ. The interaction with Tr1 cells may allow interleukin ...

Five other patients with DLBCL had lymphoma that had relapsed 10 months or less after ASCT as their last treatment ... Fig 2. Chimeric antigen receptor (CAR) targeting CD19 (CAR-19) T cells eradicated ...