Cellular clean-up: Solving the mystery of how cells initiate their recycling process
A new discovery from an international collaborative research team has solved the mystery of how cells turn on their recycling ...
HIV protein switch may help virus squeeze into host cell nucleus
Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its ...
The EMBO Journal1d
Comparison of cable bacteria genera reveals details of their conduction machinery
This study uncovers key morphological and ultrastructural similarities between cable bacteria genera. The periplasmic ...
Inability of cells to recycle fats can spell disease: Study reveals how a protein helps transport fats out of lysosomes
Accumulation of fat molecules is detrimental to the cell. Researchers from the Yong Loo Lin School of Medicine, National ...
eLife7d
Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice
This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...
rheumatologyadvisor7d
FDA Extends Review of Elamipretide for Barth Syndrome
The FDA has extended the review period for the New Drug Application for elamipretide for the treatment of Barth syndrome.
Medical Xpress22d
Energy supercomplex promises better options for heart disease treatment
They found that the formation of SC-XL increases the number of folds in the inner mitochondrial membrane, expanding its surface area. As a result, more energy-producing proteins can be embedded in ...
Science Daily23d
Recommendations for mitochondria transfer and transplantation research
recent studies of mitochondrial transfer and development of therapeutic approaches, including cell engineering and clinical trials for children requiring extracorporeal membrane oxygenation.
C&EN26d
Synergistic Enhancement of Ferroptosis via Mitochondrial Accumulation and Photodynamic-Controlled Release of an Organogold(I) Cluster Prodrug
Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China CAS Key Laboratory for ...
C&EN27d
Pulsatile Ion Transport in Nanofiltration Membranes Coupled with Electrically Tunable Pore and Hydroxyl Electrostatic Interactions
State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China University of Chinese Academy of Sciences, ...