Researchers reveal that mitochondria in photoreceptor cells align side-by-side via specialized tethers, enabling ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The mitochondrial calcium uniporter channel ...

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...

This fundamental study combines in vitro reconstitution experiments and molecular dynamics simulations to elucidate how membrane lipids are transported from the outer to the inner membrane of ...

In biology classes from high school through university, I learned that mitochondria are little objects that reside within ...

My search for answers to these stupendously ambitious questions led me, it now seems inexorably, to mitochondria. This idea ...

When the inner membrane fusion protein Opa1 level was lowered or was greatly elevated, transient fusions could occur, whereas complete fusions disappeared. Furthermore, transient fusions began from ...

The circulating fatty acid concentration also is increased after ischemia. 17 The harnessing of chemical energy by mitochondria as an inner membrane potential requires the inner membrane to have ...

MicroRNAs (miRNAs) are small non-coding RNA molecules that are known to regulate gene expression in their target locations thereby contributing to epigenetic mechanisms associated with disease ...

Moreover, metfornin was observed to reduce the formation of mitochondria-associated membranes (MAMs), which is a process that is intricately linked to the onset of ferroptosis. Significantly, Western ...