Cardiac problems associated with vascular endothelial growth factor inhibitors occur frequently in patients with cancer.

After decades of work, Dr. Folkman and his team are now watching as clinical trials begin with two recently discovered angiogenesis inhibitors, endostatin and angiostatin. In this interview ...

Figure 2: Trans-dominant inhibition of proangiogenic integrins ... play both positive and negative roles in different phases of angiogenesis and/or could act as balancers or integrators of ...

Tumor invasion and angiogenesis are reduced, although with uncomfortable side effects, by the administration of synthetic inhibitors of matrix metalloproteinases (MMPs). Our findings show that ...

Bid HK, Phelps DA, Xiao L, Guttridge DC, Lin J, London C, Baker LH, Mo X, Houghton PJ. The Bromodomain BET inhibitor JQ1 Suppresses Tumor Angiogenesis in Models of Childhood Sarcoma. Mol Cancer Ther.

The U.S. Food and Drug Administration has approved Jobevne (bevacizumab-nwgd), a biosimilar to Avastin (bevacizumab) for ...