Machine learning models have seeped into the fabric of our lives, from curating playlists to explaining hard concepts in a ...

Clinical trial to evaluate the safety and efficacy of YK012 in primary membranous nephropathy- Globally, this is the first bispecific CD19-directed CD3 T cell engager immunotherapy for this autoimmune ...

We evaluated slice cultures with single and multiplex immunohistochemistry, in situ hybridisation ... The antitumour effects of αIL-10 were reversed by major histocompatibility complex class I or II ...

The review examined the potential of combining checkpoint blockade therapy within situ vaccination as ... considerable heterogeneity and complex mechanisms of immune evasion.

“Our efforts reveal the potential of open-source AI tools to transform how we predict survival and immunotherapy benefits by detecting critical immune structures like TLS with unprecedented ease ...

They said the tumor microenvironment “facilitates a complex, dynamic ... to create a protective niche from eliciting an immune response,” they wrote. Thus, they said, targeting the immune ...

KEYNOTE-826: Final overall survival results from a randomized, double-blind, phase 3 study of pembrolizumab + chemotherapy vs placebo + chemotherapy for first-line treatment of persistent, recurrent, ...

The cytokine interleukin-15 (IL-15) plays a crucial role in the immune system by affecting the ... ANKTIVA is a first-in-class IL-15 agonist IgG1 fusion complex, consisting of an IL-15 mutant ...

The scientists discovered that repetitive HIV vaccinations can lead the body to produce antibodies targeting the immune complexes already bound to the virus. Their finding is published in Science ...

Marketing authorization application for BCG Unresponsive Non-Muscle Invasive Bladder Cancer (NMIBC) with Carcinoma in situ (CIS) submitted to European Medicines Agency (EMA) in December 2024 and ...

Through crosslinking and docking, we identify a CD3ε′-CD3γ-CD3ε-CD3δ arrangement situated around the αβTCR in situ ... in immune receptors. Using this technique, this study shows that the ...