Since the discovery of penicillin nearly a century ago, antimicrobial resistance (AMR) has become a stealthy, pervasive enemy ...

Suzhou Sanegene Bio Inc. has gained clinical trial approval in China for SGB-3383 for the treatment of complement-mediated kidney diseases, including IgA nephropathy, C3 glomerulopathy, immune complex ...

Both IC-MPGN and C3G are types of membranoproliferative glomerulonephritis (MPGN). Both conditions occur when proteins in the immune system break down. This breakdown causes deposits to build up ...

Suggested remit: To appraise the clinical and cost effectiveness of pegcetacoplan within its marketing authorisation for treating primary complement 3 (C3) glomerulopathy and primary immune-complex ...

Discovered by Novartis, Fabhalta is also being studied in a broad range of other rare kidney diseases, including atypical hemolytic uremic syndrome (aHUS), immune complex membranoproliferative ...

Dublin, Dec. 12, 2024 (GLOBE NEWSWIRE) -- The "Immune Complex Membranoproliferative Glomerulonephritis (IC-MPGN): Market Insights, Epidemiology and Forecast to 2034" report has been added to ...

More information: Anne-Laure Leblond et al, HEV ORF2 protein-antibody complex deposits are associated with glomerulonephritis in hepatitis E with reduced immune status, Nature Communications (2024).

As such, glomerulonephritis can be broadly classified as immune-complex glomerulonephritis (including infection-related glomerulonephritis, IgA nephropathy, lupus nephritis, and cryoglobulinaemic ...

Immune complex-mediated membranoproliferative glomerulonephritis (iMPGN) can develop in association with autoimmune diseases such as primary biliary cholangitis (PBC), a chronic cholestatic liver ...