Type I allergy, an IgE antibody triggered hypersensitivity disease, represents a common public health problem affecting about one third of the world´s population. Upon exposure to allergens, IgE ...

WATERTOWN, Mass.--(BUSINESS WIRE)--Seismic Therapeutic, Inc., the machine learning immunology company, today announced the presentation of preclinical data for its immunoglobulin E (IgE) protease ...

Expert Rev Clin Immunol. 2013;9(3):211-216. Atopic dermatitis is a chronic inflammatory skin disease that commonly begins in early infancy, runs a course of exacerbations and remissions and is ...

An allergic inflammatory response is a sequential interaction between various inflammatory and structural cells through their chemical messengers, which together lead to symptoms of allergy.

Histamine makes lots of changes in your body. It adjusts your blood vessels and tissues so more immune cells can rush to the area. It makes a bunch of mucus. It tells the muscles in your airways, ...

Mast cells, particularly the MCTC subtype found in the skin, are central to the pathogenesis of CSU. Their activation occurs via immunoglobulin E (IgE)-dependent receptors as well as via other ...

Phase III REMIX-1 and REMIX-2 trials demonstrated that remibrutinib, an oral BTK inhibitor, significantly reduced chronic ...

In this randomized controlled trial, among patients with chronic spontaneous urticaria who continue to have symptoms while on ...

Scientists have discovered that psychological stress can induce immune responses to food that can cause symptoms when that ...

By reducing free IgE, down-regulating high-affinity IgE receptors and limiting mast cell degranulation, Xolair minimises the release of mediators throughout the allergic inflammatory cascade. Food ...