The antigen-binding site of the antibody has a unique structure that allows it to bind ... coated with host IgA, and that these IgA-coated BEV may activate CD89 + immune cells to aggravate ...

Some practitioners argue that method of treatment claims are easier to obtain for structure–function-defined antibodies, but recent USPTO prosecution histories show that these claims also face ...

White circles represent hypothetical ancestors. Colors indicate nasal (red) and splenic (blue) antibodies. Circles and squares indicate IgA and IgG, respectively. Fig. 3. Characterization of ...

Lastly, the authors used a competitive ELISA assay to show that multimerization could improve the neutralizing capacity of these antibodies. The strength of this paper is the cloning of multiple IgA ...

Department of Chemistry, University of Bath, Claverton Down, Bath BA2 7AX, U.K. Department of Chemistry, University of Bath, Claverton Down, Bath BA2 7AX, U.K. ART-AI, Department of Computer ...