Muscimol, a GABA-A (GABAA) receptor agonist, enhances GABA's inhibitory effect on neuronal activity by activating GABAA ...

This research utilized the BioCAM DupleX and CorePlate ™ 1W 38/60 to gather high-resolution electrophysiological data for characterizing an ACROBiosystems human iPSC-derived cerebral organoid.

The increasing implication of glial cells in neurodegenerative diseases makes them an appealing addition to iPSC-based model systems for investigating ... neurons and complex 3D organoid cultures with ...

While no model perfectly recapitulates the full complexity of a disease, the application of iPSC-derived organoid co-culture approaches to primary patient-derived cells offers a valuable way to study ...

which is crucial for the study of HDLS using human forebrain organoid models. The use of corrected isogenic iPSC lines as controls increases the validity of the mutation-specific observations. In ...

An international team of researchers led by Max Delbrück Center Scientific Director Professor Maike Sander, MD, has for the first time developed an organoid model of human pluripotent stem cell ...

The research team now plans to further develop the organoid models in terms of complexity and make them available to the scientific community. "It is particularly important to us to make our ...

The world’s largest bat organoid platform, which promises improvement in the study of zoonotic viruses, has been newly developed by scientists at the Institute for Basic Science (IBS ...

An international research team has developed an innovative organoid research platform that allowed them to closely investigate the cellular antiviral defense mechanisms of mucosal epithelial ...