Humanized mice, developed by transplanting human cells into immunodeficient NSG mice to recapitulate the human immune system, are utilized in basic life science research and preclinical trials of ...

This important study utilizes humanized mice, in which human immune cells are introduced ... or incubated with apoptotic (irradiated at 30Gy) NSG mouse DCs for 12h for indirect presentation of mouse ...

Noah’s Ark is just sitting there waiting to be excavated right now. Hopefully Turkey will allow work to begin before it is too late.

Genetically engineered woolly mice could one day help populate the Arctic with hairy, genetically modified elephants and help stop the planet warming. Those are the startling claims being made by ...

Polyglutamine (polyQ) diseases, a group of dominantly inherited CNS disorders, are caused by an abnormal expansion of ...

"We are currently assessing exposure of short term (several weeks or less) androgens on reproductive parameters of female mice to model transgender men [human females on testosterone], but many ...

Methods: Here, we assess the efficacy of clinically usable CAR-engineered NK cell line NK-92/5.28.z against ErbB2-positive RMS in vitro and in a metastatic xenograft mouse model. Results: Our results ...

In NSG mice xenografted with ErbB2+ RMS, a single injection of either CAR-effector cells strongly impeded metastatic tumor development and significantly improved survival. Conclusion: Our results ...