This study presents an important finding on the role of GATA4 in aging and OA-associated cartilage pathology. The evidence supporting the conclusions is compelling, with rigorous in vitro and in vivo ...

The authors confirm that telomeres in telomerase-positive cells terminate with 5'-ATC in a Pot1-dependent manner, and demonstrate that this principle holds true in telomerase-negative ALT cells as ...

Clinical programs on track, with two major milestones later this year, and cash position, CHF 131 million as of March 31, 2025, expected to provide funding well into 2027IND filing and initial clinica ...

Researchers developed a new machine learning method that, given a relevant amino acid sequence, can automatically predict the location of a protein in any human cell line down to the single-cell level ...

Get Instant Summarized Text (Gist) LINE-1 retrotransposons, or "jumping genes," can infiltrate the human genome by binding to DNA during cell division, when the nuclear envelope temporarily breaks ...

By making these retinal pigment epithelium (RPE) cells visible, researchers have created implications for early detection of ...

Imagine cells navigating through a complex maze, guided by chemical signals and the physical landscape of their environment.

Excessive sequestration of KEAP1 into phase-separated p62 bodies under conditions of impaired autophagy drives persistent ...

Docling uses state-of-the-art models for layout analysis and table structure recognition to transform unstructured documents ...

T therapies is an expensive business. The fundamental problem is that CAR-T production is not a good fit for centralized manufacturing.