Replacing defective microglia can halt ALSP—a fatal neurodegenerative disease—in mice and humans, offering hope for broader brain therapies.

Using newly developed mouse models and a microglia replacement strategy, researchers show that bone marrow transplantation could be used as an ...

A groundbreaking study led by Prof. Bo Peng at Fudan University demonstrates that microglia replacement effectively halts the ...

In a discovery that could reshape approaches to regenerative medicine and bone repair, researchers have found that human stem ...

Mayo Clinic physician and researcher Dr. Abba Zubair's work combines two passions—medicine and space—for the benefit of astronauts and people on Earth. His research in space is yielding discoveries in ...

Allogeneic cell therapies are advancing in clinical trials, requiring oncologists and pathologists to understand the ...

Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a progressive neurological disease with an average age of onset of ...

A new study reveals that Stone Age humans in Germany operated a 'fat factory' to extract nutrients from animal bones.

Researchers at Cincinnati Children’s Hospital Medical Center have developed a new human cell model for VEXAS syndrome, a rare, severe disorder marked by systemic inflammation, bone marrow failure and ...

I was flooded with tenderness for my unborn child, along with a feeling of protectiveness for my sister and people like her who had been born with a disease but whose existences weren’t defined by it.

The triggering receptor expressed on myeloid cells 2 (TREM2) plays a pivotal role in the activation of myeloid cells and is currently being investigated as a potential therapeutic target in several ...

The remains of extinct Homo erectus dredged from the seabed off Java, along with thousands of animal fossils, are revealing a long-lost ecosystem.