The UNC technology, developed by Pediatrics Professor Chengwen Li, M.D., Ph.D., uses adeno-associated viruses (AAVs) to ferry ...

The authors confirm that telomeres in telomerase-positive cells terminate with 5'-ATC in a Pot1-dependent manner, and demonstrate that this principle holds true in telomerase-negative ALT cells as ...

(Reuters) - The United States Food and Drug Administration approved Abeona Therapeutics’ gene therapy for a rare skin disorder on Tuesday. Shares of the Cleveland-based drugmaker rose 13 per cent in ...

Homologous recombination deficiency (HRD ... of patients without pathogenic mutations in known HR genes but exhibiting genomic scars indicative of HRD led to the FDA approval of the first scar-based ...

The mechanisms of homologous recombination deficiency (HRD) in non-small cell lung cancer (NSCLC) remain understudied, mainly due to the low prevalence of germline or somatic mutations in relevant ...

With this patent, Hoth now has exclusive rights to develop and commercialize ASO-based therapies targeting the KIT gene. Hoth Therapeutics is a clinical-stage biopharmaceutical company focused on ...

Department of Chemistry, Shanghai Stomatological Hospital, State Key Laboratory of Molecular Engineering of Polymers and Institute of Biomedical Sciences, Fudan University, Shanghai 200433, People’s ...