The mitochondrion plays critical roles in cellular function, making it a prime organelle to target for fundamental studies, ...

The FDA has cleared the investigational new drug (IND) application of LP-184 in triple negative breast cancer (TNBC) treatment – a novel small molecule advanced and developed with Lantern’s AI ...

Ironically, the latest technique for producing transgenic cattle is based on a ... in livestock genomes. Genes can be introduced into nuclear donor cells by homologous recombination, thus ...

DNA (deoxyribonucleic acid) is the nucleic acid polymer that forms the genetic code for a cell or ... of X family DNA polymerases in non-homologous end joining (NHEJ) is unclear.

Bionova Scientific, an Asahi Kasei boutique commercial-scale biologics contract development and manufacturing organization (CDMO), announced it has licensed ATUM’s proprietary Leap-In Transposase ...

Effective mucosal immunity in the intestine involves a fine balance between tolerance of the microbiome, recognition and elimination of pathogens, and inflammatory tissue injury. The anti-inflammatory ...

The study is being conducted in the untreated eye of patients who have already received adeno-associated-virus-based gene therapy for ... treatment options targeting the disease.

a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the amount of blood the ... Oct. 28, 2024 ...

This manuscript characterizes a mutated clone of RNA polymerase I in yeast, referred to as SuperPol, to understand the mechanisms of RNA polymerase I elongation and termination. The authors present ...

and previous biofoundry workflows for automated HR-based DNA assembly; supporting text describing a protocol to generate a mapping file using ChatGPT (PDF) Sequence files of the plasmids used in this ...

Ferring Pharma’s Adstiladrin is a non-replicating (cannot multiply in human cells) adenoviral vector-based gene therapy. Its safety and efficacy was evaluated in a multi-centre clinical study of ...