This article examines examples of homozygous gene variants and their risk factors. We also look at how a heterozygous mutation differs from a homozygous mutation. Homozygous, or homozygosity ...

When people inherit the condition via their genes, it can be heterozygous or homozygous. “Heterozygous” means the person only has one copy of a gene that causes hemochromatosis, rather than two.

Let’s explore what it means to be heterozygous and the role it plays in your genetic makeup. A homozygous genotype is the opposite of a heterozygous genotype. If you’re homozygous for a ...

Read on to learn about the homozygous genotype, along with examples and disease risks. The term “heterozygous” also refers to a pair of alleles. Unlike homozygous, being heterozygous means you ...

There are many things that play a role in general hypercholesterolemia and heterozygous FH. These factors do play a role. One interesting fact about FH in general and homozygous FH in particular ...

This paper reports the results of a study of the frequency of heterozygous and homozygous alpha1-antitrypsin deficiency in patients hospitalized with pulmonary emphysema at a Veterans ...

When you have homozygous familial hypercholesterolemia, you inherit two copies of a gene that isn't working right, one from each of your parents. You may hear the term heterozygous familial ...

The C677T in the gene that encodes MTHFR decreases the activity of the enzyme by 35 percent in persons who are heterozygous for the mutation and by 70 percent in those who are homozygous.

What Is Heterozygous Familial Hypercholesterolemia ... You may hear about a disease with a similar name called homozygous familial hypercholesterolemia (HoFH). It differs from HeFH in the way ...

The authors describe a fast, reliable, nonradioactive method that combines PCR with capillary electrophoresis to determine genotypical differences among heterozygous (+/op), homozygous (op/op ...

Statins lower plasma cholesterol by upregulating LDL receptor gene expression and are consequently relatively ineffective in homozygous familial hypercholesterolemia (HoFH). The standard treatment ...